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Seeding the meiotic DNA break machinery and initiating recombination on...

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Replication protein-A, RPA, plays a pivotal role in the maintenance of...

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Synthetic intrinsically disordered protein fusion tags that enhance protein...

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Molecular basis for differential Igk versus Igh V(D)J joining mechanisms

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Characterization and regulation of cell cycle-independent noncanonical gene...

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Bridge RNAs direct programmable recombination of target and donor DNA

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Structural mechanism of bridge RNA-guided recombination

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Enhanced recombination empowers the detection and mapping of Quantitative...

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Seamless site-directed mutagenesis in complex cloned DNA sequences using the...

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RNA-guided recombination

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Homing gene drives can transfer rapidly between Anopheles gambiae strains...

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FIGNL1-FIRRM is essential for meiotic recombination and prevents DNA...

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STRAIGHT-IN: a platform for rapidly generating panels of genetically modified...

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Bioinformatics advances in eccDNA identification and analysis

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Cryo-EM structures of the Spo11 core complex bound to DNA

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Rapid homologue juxtaposition during meiotic chromosome pairing

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53BP1 deficiency leads to hyperrecombination using break-induced replication...

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AAV gene therapy for Duchenne Muscular Dystrophy: lessons learned from a...

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Variable orthogonality of serine integrase interactions within the ϕC31 family

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Old enlarged nucleoli open the door to the cell’s demise

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Direct observation of subunit rotation during DNA strand exchange by serine...

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Complete human recombination maps

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RECQ4-MUS81 interaction contributes to telomere maintenance with implications...

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Intercellular bridges are essential for transposon repression and meiosis in...

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Reconstitution of SPO11-dependent double-strand break formation

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PBRM1 directs PBAF to pericentromeres and protects centromere integrity

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Monoclonal antibody generation by controlled immunoglobulin gene rearrangements

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Aberrant activation of chromosome asynapsis checkpoint triggers oocyte...

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Discovery of the widespread site-specific single-stranded nuclease family Ssn

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Genomic determinants of antigen expression hierarchy in African trypanosomes

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